精神病临床高危人群的发病预测模型研究进展

Predictive model of clinical high risk for psychosis： a review of the literature

精神病临床高危人群指的是近期（多指定为一年内）出现精神病性症状，但程度较轻，且具有自知力的群体。为了加强对精神病临床高危患者的预防，多项研究致力于利用多变量临床预测模型在个人水平上评估高危患者发展精神病的风险。现对精神分裂症临床高危人群预测模型方面的研究进展进行综述。

The concept of clinical high risk （CHR） for psychosis refers to facilitate early detection and intervention and is defined by a cluster of subthreshold psychotic symptoms recently （in a year）. To enhance the indicated prevention in patients with CHR for psychosis, recent research efforts have been increasingly directed to estimate the risk of developing psychosis on an individual level by using muhivariable clinical prediction models.