磁共振质子波谱分析首发精神分裂症患者脑内谷氨酸能水平的研究进展

Research progress of magnetic resonanceproton spectroscopic analysis of glutamate level in first episode schizophrenia

随着神经影像学在精神分裂症中的研究不断发展，对精神分裂症的病因假说相关的神经生化递质也不断深入，谷氨酸作为精神分裂症病因学假说的重要补充，在精神分裂症病理生理机制中有着至关重要的地位。现对磁共振质子波谱的基本原理及其分析首发精神分裂症患者脑中谷氨酸能水平的研究进展作一综述。

With the continuous development of neuroimaging research in schizophrenia, the neurotransmitters related to the etiology of schizophrenia are also deepening. As an important complement to the etiology of schizophrenia, glutamate plays a crucial role in the pathophysiology of schizophrenia. This article mainly introduces the basic principles of magnetic resonance proton spectroscopy and the research progress on analyzing glutamatergic levels in the brain of first-episode schizophrenic patients.