卡前列素氨丁三醇治疗前置胎盘产后出血效果观察

Clinical effects of carboprost tromethamine injection on postpartum hemorrhage of placenta previa

目的探讨卡前列素氨丁三醇治疗前置胎盘产后出血的临床效果。方法选取前置胎盘产后出血患者72例,随机将其分为观察组与对照组,每组36例。对照组患者采用缩宫素治疗,观察组患者采用卡前列素氨丁三醇治疗。统计并比较两组患者产后出血量、不良反应与临床疗效。结果治疗后,观察组治疗总有效率高于对照组,产后2 h、24 h出血量均少于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率与对照组比较,差异未见统计学意义(P>0.05)。结论采用卡前列素氨丁三醇治疗前置胎盘产后出血患者能有效促进子宫收缩,减少产后出血量,提高患者临床疗效,且安全性较高,值得临床推广使用。

Objective To investigate the clinical effects of carboprost tromethamine injection on postpartum hemorrhage of placenta previa. Methods A total of 72 patients with postpartum hemorrhage of placenta previa were selected and randomly divided into the observation group and the control group, with 36 cases in each group. The patients in the control group were treated with oxytoein, and the pa- tients in the observation group were treated with carboprost tromethamine injection. The amount of post- partum hemorrhage, the adverse reaction and the clinical effects were compared between the two groups. Results After treatment, the total effective rate of the obsmwation group was higher than that of the con- trol group, and the bleeding volume of 2 h and 24 h after delivery were less than those of the control group, and the differences were significant （ P 〈 0.05 ）. There were no significant difference in the ad- verse reactions between two groups （P 〉0.05）. Conclusions In the treatment of patients with postpar- tum hemorrhage of placenta previa, carboprost tromethamine injection can effectively promote uterine con- traction, reduce the amount of postpartum hemorrhage, improve the clinical efficacy and has high safety, which is worthy of clinical application.