2型糖尿病伴复杂肝胆管结石症患者LC+LCBDE术后并发症研究

Study of Postoperative Complications of LC+LCBDE in Patients with Type 2 Diabetes Complicated with Complicated Hepatolithiasis

目的:探讨2型糖尿病伴复杂肝胆管结石症患者LC+LCBDE与复杂肝胆管结石症患者LC+LCBDE术后并发症差异。方法:选取2015年7月-2016年12月本院收治的复杂胆总管结石120例作为研究对象,根据术前是否伴有T2DM分为研究组(32例伴有T2DM)与对照组(88例不伴T2DM)。两组均采用LC+LCBDE手术治疗。比较两组近期并发症及远期并发症发生率。结果:研究组术后切口感染、高淀粉酶血症、肝功能损伤、术后低血糖及术后应激性高血糖发生率显著高于对照组,研究组寒颤发生率显著高于对照组,差异均有统计学意义(P<0.05)。结论:T2DM伴复杂肝胆管结石症患者LC+LCBDE术后切口感染、高淀粉酶血症、肝功能损伤、术后低血糖、术后应激性高血糖及寒颤发生率显著上升。

Objective：To investigate different of the postoperative complications of LC＋LCBDE in patients with type 2 diabetes complicated with complicated hepatolithiasis and complicated hepatolithiasis.Method：A total of 120 cases of complicated common bile duct stones treated in our hospital from July 2015 to December 2016 were selected,they were divided into study group（32 cases associated with T2DM）and control group（88 cases without T2DM）according to whether associated with T2DM.All were treated by LC＋LCBDE.The incidence of early complications and long-term complications were compared between the two groups.Result：The incidence of postoperative incision infection,hyperamylasemia,hepatic injury,postoperative hypoglycemia and postoperative stress hyperglycemia in the study group were higher than those in the control group,the incidence of chills in the study group was higher than those in the control group,the differences were statistically significant（P〈0.05）.Conclusion：The incidence of postoperative incision infection,hyperamylasemia,hepatic injury,postoperative hypoglycemia,postoperative stress hyperglycemia,and postoperative chills in patients with type 2 diabetes complicated with complicated hepatolithiasis are significantly increased after LC＋LCBDE.