早期外周静脉营养联合微量喂养治疗极低出生体重早产儿的临床疗效

Clinical efficacy of early peripheral vein nutrition combined with micro-feeding in the treatment of very low birth weight premature infants

目的:观察早期外周静脉营养联合微量喂养治疗极低出生体重早产儿的临床疗效。方法:选取80例极低出生体重早产儿,随机分为观察组和对照组,各40例。对照组给予全静脉营养治疗,观察组给予早期外周静脉营养联合微量喂养治疗,比较其临床效果及并发症发生情况。结果:与对照组比较,观察组的平均每天体重增加量明显升高,达到完全肠内营养时间、静脉营养时间及平均住院时间均明显缩短(均P<0.01)。观察组并发症发生率12.5%,明显低于对照组并发症发生率27.5%,差异有统计学意义(P<0.01)。结论:早期外周静脉营养联合微量喂养治疗极低出生体重早产儿疗效显著,并发症发生率低,值得临床推广应用。

Objective To observe the clinical efficacy of early peripheral vein nutrition combined with micro-feeding in the treatment of very low birth weight premature infants. Method 80 extremely low birth weight premature infants admitted to our hospital were selected and randomly divided into observation group and control group,with 40 cases in each group. The control group was given total intravenous nutrition therapy,the observation group was given early peripheral vein nutrition combined with micro-feeding therapy. The clinical effects and complications of the two groups were compared. Results Compared with the control group,the average daily weight gain was significantly increased,and the time to complete intestine management,intravenous nutrition and average length of stay were all significantly shortened in the observation group（ P〈 0. 01）. The incidence of complications in the observation group was 12. 5%,which was significantly lower than that in the control group（ 27. 5%）,with significant difference（ P〈 0. 01）. Conclusion Early peripheral vein nutrition combined with micro-feeding has a significant effect on the treatment of very low birth weight premature infants,and the incidence of complications is low,which is worthy of clinical application.