蛤蚧肽药理活性及其分子鉴定技术研究

Pharmacological activities and molecular identification of Gekko Gekko peptide

蛤蚧作为传统中药,主要活性成分有功能蛋白质、性激素样化合物、脂类等,蛤蚧肽的药理活性主要有抗感染、调节脂质代谢、抗肿瘤、激素样作用等,除药用价值外,还具有保健食品功能,功效为补肾益肺、纳气定喘、助阳益精。目前对蛤蚧肽类物质的研究非常火热,药材短缺,市场上供不应求,时常有伪混品加入。为达到快速鉴定,以供应蛤蚧的研发以及治疗,归纳整理蛤蚧肽的药理活性以及从分子生物学角度的鉴定技术,为蛤蚧肽的研发作一参考。

As a traditional Chinese medicine, Gekko gecko has main active components such as thnctlonal proteins, sex hormone like compounds, lipids, etc. The pharmacological activities of Gekko gecko peptide mainly include anti-infection, regulating lipid metabolism, anti-tumor, hormone like action, etc. In addition to medicinal value, it also has the function of health food, efficacy for tonifying the kidney and the lung, invigorating qi and relieving asthma, aiding yang and supplementing essence. At present, the research of Gekko gecko peptide is very hot, the medicine is short, the market is in short supply, and the pseudo-mixture is often added. In order to obtain rapid identification, the pharmacological activities of Gekko gecko and the identification techniques from the point of view of molecular biology were summarized in order to provide a reference for the research and development of gecko peptides.