语言认知神经科学研究中的脑沟形态分析

Application of sulcal morphometry analysis in cognitive neuroscience of language

语言是人类最重要的能力,神经影像学通过多种方式探讨其神经生理学基础。近年来,精神和神经疾病患者中报告了脑沟形态异常,启发研究者进一步探讨皮层表面精细形态特征与语言等认知能力的关系。我们总结了脑沟形态分析的主要方法,并探讨了其在语言认知神经科学中的应用现状及今后可能的研究方向。通过整合脑沟形态及多模态数据,能够帮助研究者全面理解语言认知能力和大脑结构的关系。

Language was the most remarkable ability of human beings. Numerous neuroimaging studies attempted to investigate its neurophysiological basis. Recent findings of abnormal sulcal patterns in psychiatric syndromes and neurological disorders shed new light on the relationship between language ability and complicated morphology of cerebral cortex. Here we described the studies using sulcal morphometry analysis in cognitive neuroscience of language and outlined some possible research directions for further studies. Combining sulci quantification with multimodal data will contribute to a better understanding of the neural mechanisms of language ability.