维生素D缺乏与Graves病相关性的研究进展

Research progress on the relationship between vitamin D deficiency and Graves' disease

维生素D作为维持机体钙磷代谢平衡的重要激素,对机体骨与矿物质盐代谢起着重要的调节作用。近年来研究发现Graves病患者体内维生素D水平偏低,这可能预示着Graves病患者机体内将出现一系列骨代谢紊乱的发生,测量Graves病患者体内维生素D水平,有助于Graves病相关骨质疏松的治疗和预防。此外,还有研究者发现维生素D缺乏可能参与Graves病的发生发展,而补充维生素D可能有助于Graves病的预防和治疗。本文将对维生素D与Graves病相关性及其可能存在的机制的研究新进展进行综述。

Vitamin D plays an important role in regulating the metabolic balance of calcium and phosphorus.In recent years, studies have found that vitamin D level in patients with Graves’ disease was lower, which indicate that a series of bone metabolic disorders could occur in these patients.Therefore, measuring vitamin D level in patients with Graves’ disease may help to treat and prevent osteoporosis.In addition, researchers have found that vitamin D deficiency might contribute to the development of Graves’ disease.Thus vitamin D supplementation could also prevent and help to treat Graves’ disease.In this paper, we reviewed the research progress of the relationship between vitamin D and Graves’ disease, and the mechanism that may exist.