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血清TK1、D-D、β_2-MG、LDH联合检测在非霍奇金淋巴瘤患者预后评估中的应用价值 被引量:3

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摘要 目的探讨血清TK1(胸苷激酶1)、D-D(D-二聚体)、β_2-MG(β_2-微球蛋白)、LDH(乳酸脱氢酶)联合检测在非霍奇金淋巴瘤(NHL)患者预后评估中的应用价值。方法选取郑州市第一人民医院经病理组织证实为NHL患者31例作为观察组,另选取同期门诊30例健康体检者作为对照组。检测对比两组TK1、β_2-MG、LDH、D-D水平。并比较观察组不同预后效果血清TK1、β_2-MG、LDH、D-D水平变化。结果观察组血清TK1、β_2-MG、LDH、D-D水平均高于对照组,差异有统计学意义(P<0.05);治疗后,31例NHL患者中完全缓解21例、未缓解10例;完全缓解组TK1、β_2-MG、LDH、D-D水平低于未缓解组,差异有统计学意义(P<0.05)。结论霍奇金淋巴瘤患者血清TK1、β_2-MG、LDH、D-D水平明显升高,而预后缓解者血清各指标水平降低,可联合检测上述指标用于疾病预后评估中。
作者 王秀珍
出处 《现代诊断与治疗》 CAS 2018年第7期1084-1085,共2页 Modern Diagnosis and Treatment
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