不同病理类型结直肠息肉患者血脂水平差异

The differences of blood fat Levels in patients with different pathological types of colorectal polyps

目的:探讨不同病理类型结直肠息肉患者血脂水平的差异。方法:选取2016年3月至2017年7月肠镜检查并取活检明确诊断结直肠息肉患者90例作为观察组,根据患者病理类型分为A组(炎性息肉)、B组(增生性息肉)、C组(腺瘤性息肉),选取同期肠镜检查未见异常患者50例作为对照组,检测并比较各组患者甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C),探究不同病理类型结直肠息肉患者血脂水平的差异。结果:观察组90例结直肠息肉患者,根据病理检查结果得出,炎性息肉5例(5.6%),增生性息肉32例(35.6%),腺瘤性息肉53例(58.9%);观察组患者TG、TC、LDL-C水平均高于对照组,HDL-C水平低于对照组(P<0.05);C组患者TG水平高于A、B两组,C组患者TC水平高于A组(P<0.05),其余各组间血脂各指标比较差异均无统计学意义(P>0.05)。结论:结直肠息肉患者血脂水平升高,不同病理类型患者血脂水平不尽相同,腺瘤性息肉患者TG和TC水平较高,临床针对高血脂水平患者应积极控制和干预,以降低患者结直肠息肉发生风险。

Objective： To explore the differences of blood fat levels in patients with different pathological types of colorectal polyps. Methods：90 patients with colorectal polyps who were performed enteroscopy and whose diagnoses were confirmed through biopsy from March 2016 to July 2017 were chosen as the observation group,which was further divided into Group A（inflammatory polyps）,Group B（hyperplastic polyps） and Group C（adenomatous polyps） according to the pathological types. 50 patients of the same period,the results of whose colonoscopy were normal were chosen as the control group. The levels of triglyceride（TG）,total cholesterol（TC）,low density lipoprotein cholesterol（LDL-C） and high density lipoprotein cholesterol（HDL-C） were detected in different groups to explore the differences of blood fat levels in patients with different pathological types of colorectal polyps. Results： According to the pathological examination results,there were 5 cases of inflammatory polyps（5.6%）,32 cases of hyperplastic polyps（35.6 %） and 53 cases of adenomatous polyps（58.9 %） in the 90 cases of the observation group. The levels of TG,TC and LDL-C in the observation group were higher than those in the control group,and the level of HDL-C was lower than that in the control group（P〈0.05）. The level of TG in Group C was significantly higher than that in Group A and Group B,the level of TC in Group C was significantly higher than that in Group A（P〈0.05）,and there was no significant difference in the levels of blood lipids among the other groups（P〉0.05）. Conclusion： Patients with colorectal polyps have elevated blood lipids,and different pathological types have different blood lipid levels. Patients with adenomatous polyps have higher TG and TC levels. The high blood lipid levels in patients should be actively controlled and intervened clinically to reduce the risk of colorectal polyps.