血清硒水平和尿碘水平对甲状腺癌患病的影响研究

Influence of Serum Selenium Level and Urinary Iodine Level on Thyroid Cancer

目的探讨血清硒水平和尿碘水平对甲状腺癌患病的影响。方法以150例甲状腺癌患者为观察对象,评价患者体内血清硒水平和尿碘水平并与健康受检者进行对比。结果根据统计学分析结果显示,甲状腺癌患者血清硒水平低于健康受检者血清硒水平,差异具有统计学意义(P<0.05);甲状腺癌患者尿碘水平高于健康受检者尿碘水平,差异具有统计学意义(P<0.05)。结论血清硒水平和尿碘水平是甲状腺癌发病的影响因素,其中硒水平与甲状腺癌发病率呈负相关,尿碘水平与甲状腺癌发病率呈正相关,同时通过血清硒水平与尿碘水平监测可评价甲状腺癌发病,对预防和早期诊断具有指导意义。

Objective To investigate the effect of serum selenium level and urinary iodine level on thyroid cancer. Methods The serum selenium level and urinary iodine level of 150 patients with thyroid cancer were evaluated and compared with healthy subjects. Results According to statisticalanalysis, serum selenium level of thyroid cancer patients was lower than that of healthy subjects, the difference was statistically significant（P〈0.05）. The level of urinary iodine in patients with thyroid cancer was higher than that in healthy subjects, the difference was statistically significant（P〈0.05）. Conclusion Serum selenium level and urine iodine level are the influencing factors of thyroid cancer, in which the level of selenium is negatively correlated with the incidence of thyroid cancer, and the level of urine iodine is positively correlated with the incidence of thyroid cancer.