龙胆泻肝汤治疗老年患者肝阳上亢型高血压的疗效观察

Observation on Longdan Xiegan Tang in Elderly Patients With Liver-Yang Hyperhyperactivity Type of Hypertension

目的观察龙胆泻肝汤对老年肝阳上亢型高血压的临床疗效。方法将64例肝阳上亢型高血压的老年患者随机分为A组32例(龙胆泻肝汤+苯磺酸氨氯地平+缬沙坦)和B组32例(苯磺酸氨氯地平+缬沙坦),分别观察、记录两组治疗前及治疗4周后收缩压、舒张压及伴随症状、中医症候积分变化,并将数据行组间、组内比较。结果治疗后A、B组SBP、DBP均明显低于治疗前;治疗后SBP、DBP下降程度及症状改善差异明显,A组优于B组;两组不良反应发生率差异无统计学意义(P>0.05)。结论龙胆泻肝汤联合苯磺酸氨氯地平、缬沙坦治疗老年肝阳上亢型高血压效果良好且安全、依从性好。

Objective To observe the clinical effect of Longdan Xiegan Tang in treating elderly patients with liver-yang hyperhyperactivity type of hypertension. Methods The elderly patients with 64 cases of hyperactivity of hyperactivity of liver Yang were randomly divided into group A of 32 cases（Longdan Xiegan Tang ＋ amlodipine ＋ valsartan） and group B of 32 cases（amlodipine and valsartan）. The changes of systolic pressure, diastolic pressure, accompanying symptoms and TCM syndrome scores were observed and recorded in two groups before and after 4 weeks of treatment, and the data were compared between groups and groups. Results After treatment, SBP and DBP in group A and B were significantly lower than those before treatment, and the degree of SBP and DBP decreased and symptoms improved of group A was better than group B, both of them were changed significantly. There was no significant difference in the incidence of adverse reactions between the two groups（P〉0.05）. Conclusion Longdan Xiegan Tang Combined with amlodipine besylate and valsartan is effective, safe and compliant in the treatment of hypertension of liver yang hyperactivity in the elderly.