双黄连口服液结合康复新液治疗儿童口腔溃疡临床研究

The effect of Shuanghuanglian oral liquid combined with Kangfuxin fluid in treating children's oral ulcer

目的:探究双黄连口服液结合康复新液治疗儿童口腔溃疡的效果。方法:将60例口腔溃疡患儿作为研究对象,按照入院先后实施分组,对照组30例,给予单纯康复新液治疗;观察组30例,在对照组基础上加用双黄连口服液治疗,对两组患者治疗前后的白细胞计数、淋巴细胞比率、疼痛评分(VAS)、症状改善情况以及临床治疗情况进行综合评价。结果:观察组患者治疗后的白细胞计数、淋巴细胞比率改善显著,显著优于对照组(P<0.05),有统计学意义;观察组治疗后退热时间、溃疡愈合时间均较对照组短,VAS评分低于对照组(P<0.05),存在统计学意义;且观察组治疗后有28例患者显示有效,占93.33%,显著高于对照组的70.00%,两组差异比较有统计学意义(P<0.05);随访3个月显示观察组仅有1例复发,占3.33%,与对照组的26.67%比较差异有统计学意义(P<0.05)。结论:双黄连口服液结合康复新液治疗儿童口腔溃疡,能够促进患儿临床症状改善,缓解疼痛,复发率低,效果显著,值得应用。

Objective：to explore the effect of shuanghuanglian oral liquid combined with Kangfuxin fluid on oral ulcer in children.Methods：for treatment of oral ulcer 60 patients as the research object,according to hospital successively implementation group,control group,30 cases for pure kangfuxin liquid treatment;Observation group,30 cases in the control group on the basis of treatment with Shuanghuanglian oral liquid,on two groups of patients before and after treatment of leukocyte count,lymphocyte ratio,pain score（VAS）,symptom improvement and evaluate the clinical treatment.Results：the number of white blood cell count and lymphocyte ratio improved significantly after treatment in the observation group,which was significantly better than the control group（P〈0.05）,which was statistically significant.In the observation group,after treatment,the time of febrile fever and the healing time of ulcer were shorter than that of the control group,and the VAS score was lower than the control group（P〈0.05）,and there was statistical significance.After treatment,28 patients showed effective,93.33%,significantly higher than 70.00%in the control group,with a significant difference between the two groups（P〈0.05）,and statistically significant.The observation group was followed up for 3 months with only 1 recurrence,accounting for 3.33%,compared with 26.67%in the control group（P〈0.05）.Conclusion：Shuanghuanglian oral liquid combined with Kangfuxin fluid to treat oral ulcer in children can promote the improvement of clinical symptoms,alleviate pain,low recurrence rate and remarkable effect,and it is worth popularizing and applying.