痰热清注射液治疗上呼吸道感染风热证疗效及对患者咳痰、咽部疼痛缓解时间的影响

Values of curative effect,expectoration and pharyngeal pain remission time in wind went type upper respiratory infection with Tanreqing injection

目的:探讨痰热清注射液治疗对上呼吸道感染(URI)风热证患者疗效及症状缓解时间的影响。方法:按照随机数字表法将50例URI风热证患者均分为观察组和对照组各25例,观察组给予痰热清治疗,对照组给予利巴韦林治疗,比较两组治疗效果。结果:观察组患者中医证候总有效率显著高于对照组,差异有统计学意义(P<0.05);观察组患者治疗后主症与次症评分均显著低于对照组,退热时间、咳嗽消失时间及咽痛消失时间均显著低于对照组,差异有统计学意义(P<0.05);两组患者首诊当日退热率比较,差异无统计学意义(P>0.05);观察组患者治疗后CD4+、CD8+及CD4+/CD8+水平改善效果均优于对照组,差异有统计学意义(P<0.05)。结论:痰热清注射液治疗URI风热证疗效显著,可有效改善患者症状体征及免疫指标,缩短退热时间,值得临床应用。

Objective：To explore the influence of expectoration and symptoms remission time in wind went type upper respiratory infection（URI）with Tanreqing injection.Methods：50 cases of wind went type URI were randomly divided into observation group（25 cases）and control group（25 cases）.The observation group were treated by Tanreqing injection and the control group were treated by ribavirin.The clinical effect were observed.Results：The Chinese medicine certificate waits curative effect of observation group was higher than control group（P〈0.05）;The primary symptom and minor symptom score,abatement of fever time,cough disappeared time,sore throat disappear time for observation group were lower than the control group（P〈0.05）;There were no significant difference on the first day antifebrile rate between the two groups（P〉0.05）;The level of CD4＋CD8＋,and CD4＋/CD8＋for observation group were better than the control group（P〈0.05）.Conclusion：It has significant efficacy in wind went type URI with Tanreqing injection.It can improve the symptoms and signs,immune indice and abatement of fever time.It worth of clinical recommendations.