中药熏洗方治疗儿童过敏性紫癜临床疗效观察

Clinical observation on the treatment for Henoch-Schonlein purpura in children with Chinese medicine fumigation

目的观察中药熏洗方治疗儿童过敏性紫癜的临床疗效。方法选取2016年1月至2017年1月长春中医药大学附属医院儿童诊疗中心的过敏性紫癜患儿60例,随机分为观察组和对照组各30例。对照组主要给予常规治疗,观察组在对照组治疗基础上给予中药熏洗治疗。每日1次,每次30～40min,3d为1个疗程,治疗3个疗程。观察两组临床疗效;皮肤紫癜消退时间及关节肿痛缓解情况;两组治疗后24h内复发次数。结果经Ridit分析,观察组疗效好于对照组,关节疼痛缓解情况好于对照组,观察组较对照组24h内复发次数少,差异均有统计学意义(P<0.05)。观察组患儿皮肤紫癜消退时间为(4.23±1.04)d,少于对照组(7.87±1.80)d,差异有统计学意义(P<0.05)。结论中药熏洗方治疗小儿过敏性紫癜疗效显著,尤其在皮疹消退时间、缓解关节肿痛方面有显著的疗效,且使用方法简便易行,安全无创,值得临床上推广运用。

Objective To observe the clinical curative effect of Chinese medicine fumigation formula in the treatment of children with Henoch-Schonlein purpura.Methods From January 2016 to January 2017,60 children with Henoch-Schonlein purpura were treated at the Children＇s Medical Center of the Affiliated Hospital of Changchun University of Traditional Chinese Medicine,and they were randomly divided into observation group and control group with 30 cases each.The control group was given conventional treatment,and the observation group was given Chinese medicine fumigation treatment on the basis of the treatment for the control group：once a day,30 to 40 minutes each time,3 days as a course of treatment,and treatment lasting for 3 courses.The clinical effect of the two groups was observed;the relief time of skin purpura and joint swelling;and the number of relapses within 24 hours after treatment were also recorded.Results Ridit analysis showed that the effect in the observation group was better than in the control group,and the relief of joint pain was also better.There was fewer relapses within 24 hours in the observation group,and the difference was statistically significant（P〈0.05）.The time for purpura to disappear in observation group was（4.23±1.04）d,which was shorter than the control group,（7.87±1.80）d,and there was statistical difference（P〈0.05）.Conclusion Traditional Chinese medicine fumigation formula has significant curative effect on children with Henoch-Schonlein purpura,especially in the rash subsidence and relief time of joint swelling and pain,and the method is simple,safe and non-invasive,which is worthy of clinical application.