食管支架置入术治疗晚期食管癌的效果

Effect of esophageal stent implantation treating advanced esophageal cancer

目的探讨食管支架置入术治疗晚期食管癌的效果。方法回顾性分析我院2013年1月~2016年1月收治的82例晚期食管癌患者的临床资料,根据其治疗方法不同将其分为观察组与对照组,每组41例。对照组患者行常规化疗治疗,观察组患者行食管支架置入术治疗。比较两组患者治疗前后的吞咽困难改善情况、患者气促指数及营养状况评分、生活质量评分(SF-36)、患者治疗满意率及1、2年生存率。结果治疗前,两组患者的吞咽困难情况比较,差异无统计学意义(P>0.05),治疗后,两组患者的吞咽困难情况均改善,且观察组优于对照组(P<0.05)。观察组患者的气促指数、营养状况评分、SF-36评分均优于对照组(P<0.05)。观察组患者的治疗满意率为97.56%,高于对照组的80.49%,1年生存率为95.12%,高于对照组的78.05%,2年生存率为90.24%,高于对照组的70.73%,差异有统计学意义(P<0.05)。结论食管支架置入术治疗晚期食管癌的效果良好,可改善患者的吞咽困难症状和营养状况,提高其生活质量和治疗满意率,值得临床进一步研究应用。

Objective To investigate the effect of esophageal stent implantation treating advanced esophageal cancer.Methods The clinical data of 82 patients with advanced esophageal cancer admitted into our hospital from January2013 to January 2016 were retrospectively analyzed.According to different treatment methods,they were divided into the observation group（n=41） and control group（n=41）.In the control group,patients were treated with conventional chemotherapy,while in the observation group,patients were given esophageal stent implantation.The improvement of dysphagia before and after treatment,patients′ polypnea index and score of nutritional status,quality of life score（SF-36）,patient′s satisfaction rate for treatment,and 1 year and 2 years survival rate were compared between the two groups.Results Before treatment,there was no significant difference in dysphagia between the two groups（P〉0.05）.After treatment,dysphagia was improved in both groups,and the improvement in the observation group was better than that of the control group（P 0.05）.The polypnea index,score of nutritional status,and SF-36 score in the observation group were all superior to those in the control group（P〈0.05）.The satisfaction rate for treatment in the observation group was 97.56%,which was higher than that in the control group（80.49%）.1 year and 2 years survival rate was 95.12% and 90.24% respectively,which was higher than that of the control group（78.05% and 70.73% respectively）（P〈0.05）.Conclusion The effect of esophageal stent implantation treating advanced esophageal cancer is good.It can improve the dysphagia symptoms and nutritional status,improve the quality of life and the satisfaction rate for treatment in patients.It is worthy of further clinical study and application in clinic.