慢性心衰患者采用依伐布雷定联合美托洛尔的临床疗效

Clinical Efficacy of Ivabradine Hydrochlorid Combined With Metoprolol in Patients With Chronic Heart Failure

目的针对慢性心衰患者采用依伐布雷定与美托洛尔联合治疗的效果进行分析研究。方法收集2015年1月—2016年1月的30例慢性心衰患者有关资料进行分析研究,随机将患者平均分为三组,每组各有10例患者,A组患者采用依伐布雷定治疗,B组患者采用美托洛尔治疗,C组患者采用上述两种药物联合治疗的方法,对三组患者的治疗效果进行比较。结果治疗后,C组患者的治疗总有效率及心率变化明显比A、B两组患者好,药物不良反应发生率最低,差异具有统计意义(P<0.05)。结论慢性心衰患者采用依伐布雷定与美托洛尔联合治疗,可使患者治疗总有效率明显提升,并调节改善患者的心率变化,临床应用价值较高。

Objective To analyze the effect of combined therapy of ivabradine hydrochlorid combined with metoprolol in patients with chronic heart failure. Methods Based on the data of 30 patients with chronic heart failure were collected from January 2015 to January 2016, the patients were randomly divided into three groups, each group has 10 patients. Group A patients were treated with ovastatin, group B patients were treated with metoprolol, and group C patients were treated with the two kinds of combined therapy, and the treatment effect of the three groups was compared. Results After treatment, the total effective rate and heart rate in group C were significantly better than those in group A and B. The proportion of adverse drug reactions was the lowest among the three groups,and the difference between the two groups was statistically significant（P〈 0.05）. Conclusion The combination of the treatment of chronic heart failure with ivabradine hydrochlorid combined with metoprolol can improve the total effective rate of patients and regulate the improvement of heart rate.