云南松松塔水提物对正常及心衰家兔心脏的影响

Effects of Water Extracts from Pinus yunnanensis Cones on Normal or Failure Heart of Rabbits

研究云南松松塔水提物对正常家兔及心衰家兔在体心脏的影响。用30g/L戊巴比妥钠静脉注射制备家兔在体心衰模型,观察云南松松塔水提物对正常家兔及心衰家兔的心肌收缩张力和收缩频率的影响。结果表明,云南松松塔水提物3个剂量对正常家兔心肌收缩张力和收缩频率无影响,但对心衰家兔的心肌收缩张力和收缩频率均有增强作用。因此,一定剂量的云南松松塔水提物可加强心衰家兔的心肌收缩张力和收缩频率。

This experiment studied the effects of water extracts from Pinus yunnanensis cones on the normal or failure heart of rabbits in vivo.30 g/L pentobarbital sodium was used to produce failure heart model in rabbits.Then,the effects of water extracts fromPinus yunnanensis cones on the myocardial contractility and contraction frequency of normal or failure heart in rabbits were examined.The results showed：three doses of water extracts from Pinus yunnanensis cones had no effects on the myocardial contractility and contraction frequency of normal heart,while they could enhance these parameters of failure heart.As a result,water extracts from Pinus yunnanensis cones could enhance the myocardial contractility and contraction frequency of failure heart in rabbits within a certain dose.