慢性萎缩性胃炎中医证型与胃镜、胃黏膜病理及幽门螺杆菌感染的相关性研究

Relationship between TCM Syndrome Types of Chronic Atrophic Gastritis and Gastroscopy,Gastric Mucosa Pathology and Helicobacter Pylori Infection

目的:对慢性萎缩性胃炎(CAG)中医证型与胃镜、胃黏膜病理及幽门螺杆菌感染的相关性进行分析探讨。方法:选取本院2015年1月-2017年10月收治的110例CAG患者作为研究对象,对所有患者行中医证型分型,对证型分布特点、患者的年龄、性别、胃镜检查、幽门螺杆菌感染及胃黏膜病理检查的相关性进行分析探讨。结果:110例患者中医证型中脾胃虚弱证41例,占37.27%,明显高于其他证型。胃镜表现方面,单纯性萎缩性形态患者仅占13.64%,其中以脾胃湿热证所占比例最低。患者的萎缩多以轻、中度为主。脾胃虚弱证患者的重度萎缩比例明显低于肝胃不和证、胃络瘀血证及脾胃湿热证。幽门螺杆菌感染者为51例,占46.36%。结论:慢性萎缩性胃炎病理演变同中医证型、幽门螺杆菌感染等有着一定相关性,在病变早期以实证为主,幽门螺杆菌的感染率较低,在病变中晚期多以虚实夹杂证为主,幽门螺杆菌的感染率较高。

Objective：To analyze the relationship between TCM syndrome types of chronic atrophic gastritis（CAG） and gastroscopy, gastric mucosa pathology and Helicobacter pylori infection.Method：A total of 110 patients with CAG treated in our hospital from January 2015 to October 2017 were selected as study objects and were classified by TCM syndrome type.The distribution of syndromes,age,sex,gastroscopy,infection of Helicobacter pylori and pathological examination of gastric mucosa were analyzed and discussed.Result：Among 110 patients,41 cases of spleen-stomach weakness pattern were found in TCM syndrome types,accounting for 37.27%,which was significantly higher than that of other syndrome types.The proportion of patients with simple atrophic morphology was only 13.64%,and the proportion of spleen and stomach damp-heat pattern was the lowest.The atrophy of the patients were mainly mild and moderate.The proportion of severe atrophy in patients with spleenstomach weakness pattern was significantly lower than those of disharmony of liver and stomach,blood stasis of stomach collaterals and spleen and stomach damp-heat pattern.51 cases were infected with Helicobacter pylori,accounting for 46.36%.Conclusion：The relationship between the pathological evolution of CAG and TCM syndrome types,helicobacter pylori infection is close.The excess syndrome dominated in early lesion,the helicobacter pylori infection rate is low.The syndrome of intermingled deficiency and excess dominated in the middle and advanced stage,and the helicobacter pylori infection rate is high.