磨玻璃密度肺结节的CT征象特点及诊断价值

CT Findings of Pulmonary Ground Glass Density Nodules and the Diagnostic Value

目的探究磨玻璃密度肺结节(GGNs)的CT征象特点及诊断价值。方法回顾性分析我院收治的68例GGNs患者的病理资料及CT影像学征象,对其病灶大小、性质、有无分叶、有无毛刺、边界、空泡症、实性成分大小及实性成分含量等资料进行统计学分析。结果浸润前病变与微浸润腺癌的病灶类型、大小、有无分叶、毛刺、边界及实性成分、含量等资料具统计学差异(P﹤0.05);在支气管充气症、空泡症及胸膜凹陷症等无显著性差异(P﹥0.05);logistic回归分析显示,病灶大小、类型、有无分叶、有无毛刺及边界清晰毛糙度为浸润前病变及微浸润腺癌的独立影响因素。结论病灶大小、性质、分叶、毛刺及边界为浸润前病变及微浸润腺癌的独立影响因素,临床上可作为CT影像学诊断参考。

Objective To explore the CT findings of pulmonary ground glass density nodule（GGNs） and the diagnostic value. Methods The pathological data and CT imaging signs of 68 patients with GGNs were retrospectively analyzed. The data, such as size, nature, lobulation, burr, boundary, vocule sign, size and content of solid components were analyzed statistically. Results There were statistically significant differences in the type, size, lobulation, burr, boundary, solid components and the content between preinvasive lesions and microinvasive adenocarcinoma（P0.05）, but there was no significant difference in air bronchogram, vocule sign or pleural indentation（P0.05）. Logistic regression analysis showed that the size, type, lobulation, burr and boundary of lesions were independent influencing factors of preinvasive lesions and microinvasive adenocarcinoma. ConclusionThe size, nature, lobulation, burr and boundary are independent influencing factors of preinvasive lesions and microinvasive adenocarcinomas. They can be used as a reference for CT imaging diagnosis.