前列腺中央带前列腺癌与前列腺增生MRI弥散加权成像的多b值分析

Signal Intensity Analyzing of Multi b Values MRI in Prostatic Central Zone: Applying to Difference between Prostatic Cancer and Hyperplasia

目的分析位于中央带的前列腺癌和增生在多b值DWI的信号变化及差别,旨在提高鉴别诊断能力。方法中央带前列腺癌与增生患者分别15例和30例,均行前列腺MRI多参数扫描及从b0至b1000s/mm^29个b值DWI。以T2WI表现低信号结节为准,测量前列腺癌与增生结节在各b值的信号强度并进行统计学比较,对病变的b值大小与信号强度作相关分析,观察其散点图的分布特点。结果随着b值增加,前列腺癌的信号降低程度低于增生结节的信号降低程度;在b1000s/mm^2,前列腺癌信号高于增生结节。在b200至b1000s/mm^2,2种病变信号强度均具有显著性差异(P值均﹤0.05);而在b200s/mm^2以下,信号强度无统计学差异。在b200-b1000s/mm^2、b0-b1000s/mm^2的信号强度之差,前列腺癌低于增生结节,具有显著性差异(P值均﹤0.05),而b20-b200s/mm^2 2种病变的信号强度之差则无统计学差异。前列腺癌与增生结节的信号强度与b值具有高度的负相关(r分别=-0.952和-0.960),散点图显示随着b值增大,前列腺癌信号下降趋势较增生结节平缓。结论中央带前列腺癌和增生结节在不同b值信号强度变化具有各自的规律,在中、高b值具有显著性差异,对于T2WI低信号的良恶性病变的鉴别诊断具有价值。在低b值,2种病变的信号强度不具有统计学差异,需进一步研究2种病变的T2透射效应和血流成分的特点。

Objective Analyzing signal changing and difference of multi b values DWI between prostatic cancer and hyperplasia node lie at central zone and to evaluate ability of differential diagnosing. Methods Fifteen patients with prostatic cancers and 30 patients with hyperplasia lie at central zone were experienced multi-parameters MRI and 9 b values DWI. Standard By low signal nodes in T2 WI, the signal intensity of each b value in prostatic cancer and hyperplasia node were measured and statistically compared. The relative analyzing between b values and signal intensities were done in respectively prostatic cancer and hyperplasia and the characters of scatter maps were observed. ResultsWith b value＇s increasing, decreasing degree of signal intensity in prostatic cancer was lower than decreasing degree in hyperplasia node. In imaging of b1000 s/mm2, signal intensity of prostatic cancer was higher than one of hyperplasia node. In imaging of b200-b1000 s/mm2, the signal intensities of both diseases had marked difference（all P〈0.05）, but in imaging below b200 s/mm2, the signal intensities of both diseases had not marked difference. The signal intensities by subtracting b200-b1000 s/mm2 and b0-b1000 s/mm2 of prostatic cancer was less than one of hyperplasia node（all P〈0.05）, but in the signal intensities by subtracting b0-b200 s/mm2 there was not marked difference between both diseases. The signal intensities of prostatic cancer and hyperplasia node had highly negative relation with b value（r =-0.952,-0.960 respectively）. The scatter maps showed that with b value＇s increasing, signal intensity decreasing tendency of prostatic cancer was more slowed down than hyperplasia node. Conclusion In different b value, the changing of signal intensity in prostatic cancer and hyperplasia node lie at central zone had itself regularity and in middle and high b values, the signal intensities had marked difference which were valuable to distinguish benign disease from malignant disease displaying low signal in T2 WI. In low b values, the signal intensities both diseases had not marked difference and so studying the T2 transmitting effect and fraction of blood flowing of diseases were necessary.