缺血性脑卒中患者颈动脉斑块的弹性特征

Carotid Plaque Elasticity in Patients with Ischemic Stroke

目的缺血性脑卒中的发生与颈动脉斑块生物特性密切相关,本文探讨卒中患者颈动脉斑块的弹性特点。资料与方法回顾性分析2016年11月-2017年5月于天坛医院神经内科诊断为颈动脉粥样硬化斑块患者,采用双盲法连续纳入卒中组颈动脉斑块形成患者41例与非卒中组颈动脉斑块形成患者50例。所有患者均行常规二维超声及实时剪切波弹性成像检查,记录并分析斑块的整体杨氏模量值。结果卒中组斑块的杨氏模量为(38.41±16.30)k Pa,小于非卒中组的(51.03±21.46)k Pa,差异有统计学意义(P<0.05)。结论缺血性脑卒中患者斑块杨氏模量较非卒中组低,提示缺血性脑卒中患者斑块质地较软。

Purpose The ischemic stroke is closely related to the biological characteristics of carotid plaque. This study aims to explorethe characteristics of carotid plaque elasticity in patients with ischemic stroke. Materials and Methods Patients with carotidatherosclerotic plaque confirmed in Department of neurology, Tiantan Hospital from November 2016 to May 2017 were retrospectivelyanalyzed. A total of 91 patients with carotid plaque were included by double blind method, including 41 in symptomatic group and 50 inasymptomatic group. All the patients were examined by gray-scale ultrasound and real-time shear wave elastography. Young’s Modulus of plaques were recorded and analyzed. Results The Young’s Modulus in symptomatic group was （38.41±16.30） kPa, lower than that in asymptomatic group [（51.03±21.46） kPa], with statistically significant difference （P〈0.05）. Conclusion The Young’s Modulus of plaquein ischemic stroke patients is lower than that in control group, suggesting that the plaque in ischemic stroke patients is softer.