不同运动方式改善原发性高血压患者自主神经功能的疗效对比

Curative effect of different exercise improving autonomic nervous function in patients with essential hypertension

目的:探讨有氧抗阻运动对原发性高血压患者产生降压疗效的自主神经功能变化。方法:将106例原发性高血压患者随机分为3组,抗阻组(35例)、有氧组(36例)以及联合组(35例),3组在口服药物的基础上分别进行中等强度抗阻运动、慢跑以及有氧抗阻运动辅助治疗。疗程结束后,对3组患者进行血流动力学测定和心血管自主神经功能评测。结果:疗程结束后,3组收缩压和舒张压均明显低于治疗前(均P<0.05),联合组收缩压和舒张压均较抗阻组和有氧组低(均P<0.05);抗阻组心率变异性(HRV)-高频功率(HF)明显低于治疗前,HRV-低频功率(LF)和HRV-LF/HF明显高于治疗前,有氧组与联合组治疗后HRV-HF明显高于治疗前,HRV-LF和HRV-LF/HF治疗后低于治疗前,差异均有统计学意义(均P<0.05);3组治疗后HRV比较:3组中联合组HRVHF最高,HRV-LF、HRV-LF/HF联合组最低,其次为有氧组,3组比较差异具有统计学意义(均P<0.05);疗程结束后有氧组与联合组BPV-LF明显低于治疗前(均P<0.05),抗阻组BPV-LF较治疗前明显增高(P<0.05);3组中BPV-HF值差异无显著性(P>0.05),联合组BPV-LF值最低,其次为有氧组,抗阻组最高,3组差异有统计学意义(P<0.05)。结论:有氧抗阻运动能够明显改善患者心血管自主神经功能,优于单纯抗阻运动及有氧运动。

Objective： To explore the changes of autonomic nervous function by depressurization in primary hyper tension patients. Methods： All 106 cases of primary hypertension were randomly divided into three groups： the re sistance group （35 cases）, aerobic group （36 cases） and combination group （35 cases）. All three groups accepted o ral administration of drugs. The resistance group accepted moderate intensity resistance exercise, the aerobic group accepted jogging, and combination group accepted aerobic resistance movement additionally. After the treatment course, the hemodynamic indexes and cardiovascular autonomic nerve functions in three groups were evaluated. Results： After the treatment, systolic and diastolic blood pressure in all three groups were significantly lower than those before treatment （all P〈0.05）. Systolic and diastolic blood pressure in combination group was relatively low er than in resistance and aerobic groups （all P〈0.05）. The heart rate variability （HRV） high frequency （HF） in resistance group was significantly lower than that pretreatment, and HRV low frequency （LF） and HRV power LF/HF were significantly higher than pretreatment. HRV HF in aerobic group and combination group were signifi cantly higher and HRV LF and HRV LF/HF were significantly lower than those pretreatment （all P〈0.05）. After treatment, HRV HF was the highest and HRV LF and HRV LF/HF lowest in combination group, followed in aer obic group （all P〈0.05） ; BPV LF in aerobic group and combination group were significantly lower than pretreat ment, and BPV LF in resistance group was higher than pretreatment （all P〈0.05）. There were no significant differences among three groups （P〉0.05）. BPV LF was lowest in combination group, followed in aerobic group, and lowest in resistance group （all P〈0.05）. Conclusion： Aerobic resistance exercise can significantly improve au tonomic nervous system in patients with primary hypertension, and is superior to resistance or aerobic exercise a lone.