合并微血管病变的糖尿病患者颈动脉瞬时波强参数研究

Analysis on carotid artery transient wave intensity in diabetic patients with microangiopathy

目的探讨应用颈动脉瞬时波强(WI)参数评价合并微血管病变的糖尿病患者心血管功能的临床应用价值。方法选取我院合并微血管病变的糖尿病患者(糖尿病组)和同期健康志愿者(正常对照组)各36例,应用WI技术检测两组受检者左颈总动脉获得瞬时加速度波强(W1)、瞬时减速度波强(W2)、负向波面积(NA)、射血前期时间(R-W1)、射血时间(W1-W2)及血管僵硬度指数(β),并对其进行比较。结果糖尿病组W1和NA均显著低于正常对照组,β高于正常对照组,差异均有统计学意义(均P<0.05);W2两组比较差异无统计学意义。结论 WI各参数在早期发现糖尿病患者心血管功能异常方面发挥了一定作用。

Objective To evaluate the clinical value of cardiovascular function in diabetic patients with microangiopathy by carotid artery transient wave intensity（WI）parameters.Methods Thirty-six diabetic patients with microangiopathy（diabetes group）and 36 healthy volunteers（normal control group）were selected in our hospital.The WI technique was used to detect the transient acceleration wave intensity（W1）,transient velocity（W2）,negative wave area（NA）,pre ejection time（R-W1）,ejection time（W1-W2）and vascular stiffness index（β）in two groups,the results were compared.Results W1 and NA in diabetes group were lower than those in normal control group（all P〈0. 05）,and β was higher than that in normal control group（P〈0. 05）.There was no significant difference of W2 between two groups.Conclusion Carotid arterial WI parameters plays an important role in evaluating the impaired working condition of both heart and arterial system in diabetic patients.