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淋巴结累及野照射和预防性照射在老年食管鳞癌患者根治性单纯放疗中的应用效果对比 被引量:1

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摘要 目的:研究分析淋巴结累及野照射和预防性照射在老年食管鳞癌患者根治性单纯放疗中的临床效果。方法:选取2015年4月-2017年1月笔者所在医院收治的老年食管鳞癌的患者70例进行研究,根据治疗办法的不同将其分为对照组(35例)和试验组(35例),对照组患者采用预防性照射进行治疗,试验组采用淋巴结累及野照射进行治疗,对两组患者的治疗效果、照射肺剂量及不良反应发生情况进行分析比较。结果:两组治疗总有效率比较差异无统计学意义(P>0.05);试验组患者照射肺剂量中的靶区体积V5、V20均显著低于对照组,而V平均值明显高于对照组,比较差异均有统计学意义(P<0.05);试验组患者中放射性肺炎1~2级、3级的发生率均显著低于对照组,比较差异均有统计学意义(P<0.05);两组各级放射性食管炎及血液学毒性的发生率比较,差异均无统计学意义(P>0.05)。结论:对于老年食管鳞癌的患者采用淋巴结累及野照射和预防性照射进行放疗都具有一定的疗效,但是淋巴结累及野照射的方式中患者的肺照射剂量比较小,可大幅降低不良反应的发生率。
机构地区 安溪县医院
出处 《中外医学研究》 2018年第18期149-150,共2页 CHINESE AND FOREIGN MEDICAL RESEARCH
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