七氟烷复合瑞芬太尼对小儿麻醉苏醒期躁动的影响

Effects of sevoflurane combined with remifentanil on restlessness during anesthesia in children patients

目的探讨七氟烷复合瑞芬太尼对小儿麻醉苏醒期躁动的影响。方法选择80例拟实施扁桃体加腺样体切除手术患儿,采用随机数字表法分为试验组和对照组,每组40例。其中对照组采用七氟烷麻醉,试验组采用七氟烷与瑞芬太尼联合麻醉。对比2组患儿的苏醒时间、手术时间、躁动患儿发生比例、躁动时间大于15 min患儿的发生比例以及躁动评分。结果 2组患儿苏醒时间、手术时间比较差异无统计学意义(P>0.05);试验组麻醉苏醒期患儿躁动率、平均躁动评分均显著优于对照组,差异有统计学意义(P<0.05)。结论在患儿实施全麻进行扁桃体加腺样体切除手术治疗时给予患儿采用七氟烷与瑞芬太尼进行联合麻醉能显著降低患儿在麻醉苏醒期的躁动发生情况,有助于提高患儿的临床治疗效果。

Objective To investigate the effects of sevoflurane combined with remifentanil on agitation at stage of analepsia of anesthesia in children patients. Methods Eighty children patients who were ready to undergo tonsillectomy and adenoidectomy in our hospital were enrolled in the study. According to random number table method,these patients were divided into control group（ n = 40） and experimental group（ n = 40）. The patients in control group were treated by sevoflurane anesthesia,however,the patients in experimental group were treated by sevoflurane combined with remifentanil anesthesia. The palinesthesia time,,length of operation,the proportion of patients with restlessness,the proportion of patients with agitation 〉15 minutes and the restlessness scores were observed and compared between the two groups. Results There were no significant differences in palinesthesia time and length of operation between the two groups（ P〉0. 05）. Moreover the restlessness rate at stage of analepsia and average agitation scores in experimental group were superior to those in control group（ P〈0. 05）.Conclusion The combined anesthesia of sevoflurane with remifentanil for children patients undergoing tonsillectomy and adenoidectomy can significantly reduce the incidence of agitation of patients at stage of analepsia,which is helpful to improve clinical curative effects.