原发性高血压病人紧张状态与免疫相关指标的相关性研究

Correlation between Tension and Immune Related Indexes in Patients with Essential Hypertension

目的探讨原发性高血压病人紧张状态对免疫相关指标的影响。方法选取原发性高血压病人146例,根据是否存在紧张状态分为紧张状态组(32例)与非紧张状态组(114例)。检测并比较其免疫相关指标。结果原发性高血压紧张状态病人血清球蛋白(GLB)、免疫球蛋白G(IgG)均低于非紧张状态病人,差异有统计学意义(P<0.05),且GLB、IgG均与紧张状态呈负相关(r=-0.189,P=0.023;r=-0.223,P=0.007)。结论原发性高血压病人紧张状态易导致免疫功能下降。

Objective To investigate the effect of stress on immune-related indexes in patients with essential hypertension （EH）. Methods One hundred and forty-six patients with EH,of wich 32 patients in tension and 114 patients in non-tension state,were se-lected. The immune-related indicators were detected. Results The levels of serum globulin（GLB） and immunoglobulin G （IgG） in hypertensive patients with tension were significantly lower than those in patients with non-tension state （ P〈0.05）. There was a sig-nificant negative correlation between GLB,IgG and tension （ r=-0.189, P=0.023; r=-0.223, P=0.007）. Conclusion Tension in patients with EH can lead to the decline of immune function.