高龄急性ST段抬高型心肌梗死病人急诊PCI围术期应用比伐卢定的有效性及安全性分析被引量：5

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摘要目的探讨高龄急性ST段抬高型心肌梗死(STEMI)病人行急诊经皮冠状动脉介入术(PCI)围术期应用比伐卢定的有效性及安全性。方法筛选我院行急诊PCI术年龄≥75岁的STMEI病人85例,随机分为比伐卢定组(A组,43例)和普通肝素组(B组,42例),比较两组病人的抗凝效果、术后30 d主要心脑血管不良事件(MACE)及出血发生率。结果 A、B两组病人术中活化凝血时间(ACT)达标率比较,差异无统计学意义(97.7%与90.5%,P>0.05);B组出血事件发生率高于A组,差异有统计学意义(21.4%与4.6%,P<0.05);两组30 d的MACE发生率比较,差异无统计学意义(13.9%与16.7%,P>0.05)。结论与普通肝素相比,高龄STMEI病人行急诊PCI术中使用比伐卢定,抗凝疗效相当,但能明显减少出血事件,且未增加MACE的发生率。

作者张国江

机构地区大同市第三人民医院

出处《中西医结合心脑血管病杂志》 2018年第10期1410-1411,共2页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

关键词急性ST段抬高型心肌梗死高龄比伐卢定经皮冠状动脉介入术主要心脑血管不良事件活化凝血时间

分类号 R542.2 [医药卫生—心血管疾病] R256.2 [医药卫生—中医内科学]

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