经鼻高流量氧疗在慢性阻塞性肺疾病中的研究进展

Research Progress of High Flow Nasal Cannula in Chronic Obstructive Pulmonary Disease

慢性阻塞性肺疾病(COPD)对人类健康的威胁与日俱增,因此备受关注。而氧疗可以延缓COPD恶化的速度,提高患者生存质量,减少并发症的出现。但是,传统氧疗的治疗效果有时不尽如人意。经鼻高流量氧疗(HFNC)作为一种新氧疗方式,其高流速供氧气流可高效缓解COPD患者的缺氧和二氧化碳潴留情况,同时充分的加温、加湿效果不仅可以增强患者氧疗的舒适感,缩短治疗时间,还可降低发生呼吸道感染和支气管痉挛的概率。此外,HFNC还能推迟急性发作期COPD患者的插管时间,为控制感染赢得时间。未来,HFNC能否明显改善COPD患者的预后需进一步研究。

Chronic obstructive pulmonary disease（ COPD） has attracted increasing attention due to its increasing threat to human health. Oxygen therapy can slow down the deterioration of COPD,improve the quality of life and reduce the occurrence of complications. However,the therapeutic effect of traditional oxygen therapy is sometimes not satisfactory. The high flow nasal cannula（ HFNC）,as a new oxygen therapy,can effectively relieve the condition of hypoxia and retention of carbon dioxide in COPD patients. At the same time,the effect of heating and humidification can not only enhance the comfort of patients with oxygen therapy,shorten the time of treatment,but also reduce the incidence of respiratory infection and bronchial spasm. In addition,HFNC can delay the intubation time of COPD patients during acute attack,and gain time to control the infection. In the future,whether HFNC can significantly improve the prognosis of COPD still needs further study.