神经调节干预技术在强迫症中的应用进展

Neuromodulation Intervention in Obsessive-Compulsive Disorder

强迫症是一种较为难治的精神疾病,有相当一部分患者经充分的药物治疗和心理治疗,症状仍不能完全缓解。神经调节干预技术是一种新兴的治疗手段,具有较高的治疗潜力,近年来在强迫症中的应用取得了初步进展。神经调节干预技术包括电休克、重复经颅磁刺激以及深部脑刺激,电休克技术可选择性应用于共病其他精神障碍的患者;重复经颅磁刺激是一种非侵入性技术,可作为强迫症患者一种新的增效途径;而深部脑刺激作为一种侵入性技术,疗效确切,易被患者和医师所接受。

Obsessive-compulsive disorder（ OCD） is an intractable mental disorder. A considerable number of patients are still unable to achieve full remission after adequate medication and psychotherapy. Neuromodulation intervention is a new treatment with high potential,and preliminary progress has been made in the application for OCD in recent years. Neuromodulation interventions include electroconvulsive therapy,repetitive transcranial magnetic stimulation and deep brain stimulation. Electroconvulsive therapy can be applied to OCD comorbid other mental disorders; repetitive transcranial magnetic stimulation is a noninvasive technique that can be used as a new augmentation strategy for patients with OCD; deep brain stimulation,as an invasive technique,because of its exact efficacy,is easy to be accepted by the patients and doctors.