二维斑点追踪超声心动图对冠状动脉慢血流患者左心室收缩功能的评价

Evaluation of longitudinal left ventricular systolic function in patients with coronary slow flow using 2-dimensional speckle-tracking echocardiography

目的采用二维斑点追踪超声心动图(2-dimensional speckle-tracking echocardiography,2D-STE)评估冠状动脉慢血流(coronaryslow flow,CSF)患者左心室收缩功能,为临床提供有价值的信息。方法选择61例CSF患者,同期选择冠状动脉造影正常的患者52例。采用2D-STE测量所有患者左心室纵向应变(Globallongitudinalstrain,GLS)、左心室径向应变(Global adial strain,GRS)、左心室圆周应变(Global circumferential strain,GCS)。结果两组GCS,GRS无统计学差异(P>0.05)。与对照组比较,CSF组GLS显著减低(P<0.05)。采用GLS截点值为-16.5预测CSF的灵敏度为76.9%,特异度为67.4%,曲线下面积0.726(P<0.001)。结论冠状动脉慢血流患者左心室纵向收缩功能显著减低。

Objective The aim of this study was to evaluate the longitudinal left ventricular（LV） systolic function in the coronary slow flow（CSF） phenomenonusing by 2-dimensional speckle-tracking echocardiography（2D-STE）.Methods A total of 61 patients with CSF and 52 patients with normal coronary artery as control group were included.The LV global longitudinal strain（GLS）,global circumferential strain（GCS） and the global radial strain（GRS） were measured by 2D-STE.Results The GCS,GRS were similar between two groups（P〈0.05）,while the GLS reduced in the CSF group（P〈0.05）.Receiver operating characteristic curve analysis revealed a cut-off point of-16.5% for GLS with a sensitivity of 76.9% and a specificity of 67.4%（P0.001,AUC=0.726）.Conclusions Our results showed that the coronary slow flow phenomenon impair the longitudinal LV systolic functions.