纵隔子宫与妊娠

Septate uterus and pregnancy

子宫畸形包括一组女性生殖系统苗勒氏管的先天异常,育龄期女性中的发生率为4.3%,不孕妇女中的发生率为3.5%,复发性流产女性中为13%。纵隔子宫的胚胎存活率很低,约为5%~27%,不孕率很高,高达36%,反复流产率甚至65%以上。因此认为不良妊娠结局与异常宫腔或者异常的子宫血管相关,手术治疗这些解剖学缺陷是治疗的基础。本文从纵隔子宫对妊娠的不良影响、治疗指征及方式、治疗后的妊娠结局进行综述。

Uterine malformations include a group of congenital Mullerian duct of abnormalities of female reproductive system,and the incidence rate is 4.3% in the women of childbearing age,3.5% in infertile women,and 13% in women of recurrent spontaneous abortions.The embryo survival rate in women with septate uterus is about 5%-27%,and infertility rate is up to 36%.What is more,the rate of recurrent abortion is even more than 65%.Therefore,it is believed that the adverse pregnancy outcome is associated with abnormal uterine cavity or abnormal uterine vessels in the women with septate uterus.The surgical treatment of the anatomical defects is the basis of treatment.This article reviews the adverse effects of the uterine septum on the pregnancy,the indications and methods of treatment,and the outcome of the pregnancy after the treatment.