血常规相关衍生参数对于不同Child-Push分级肝硬化的意义

Implications of derivative parameters of routine blood tests for analysis and diagnosis on Child-push grading cirrhosis

目的探讨红细胞和血小板的衍生参数对于不同Child-Push分级肝硬化的意义。方法选取83例肝硬化患者作为研究对象,以同期30例健康体检者作为对照。入选患者按照Child-Push分级分为A、B、C组,分别检测各组红细胞计数(RBC)、红细胞平均体积(MCV)和红细胞分布宽度(RDW)、血小板计数(PLT)、平均血小板容积(MPV)和血小板分布宽度(PDW)。结果对照组、A组、B组、C组的RBC依次下降,MCV与RDW依次升高,差异均有统计学意义(P<0.05);对照组、A组、B组、C组的PLT依次下降,MPV与PDW依次升高,差异有统计学意义(P<0.05)。结论 RBC、PLT及其衍生参数对于不同Child-Push分级肝硬化的临床观察可能具有一定的指导价值。

Objective To evaluate the implications of derived parameters of red blood cells and platelets for analysis and diagnosis on Child-push grading cirrhosis. Methods 83 patients with hepatocirrhosis were chosen and divided into three experimental groups,namely,group A,group B,and group C according to the Child-push score. A total of 30 healthy subjects were chosen as the control group. Red blood cell（ RBC）,erythrocyte mean corpuscular volume（ MCV）,red blood cell distribution width（ RDW）,platelet count（ PLT）,mean platelet volume（ MPV） and platelet distribution width（ PDW） were observed. Results The RBC in the control group,the A group,the B group and the C group declined in turn（ P〈0.05）; the MCV and RDW increased in turn（ P〈0.05）. The PLT in the control group,the A group,the B group and the C group declined in turn（ P 0.05）; the MPV and PDW increased in turn（ P〈0.05）. Conclusions RBC,PLT and their derived parameters may be of guiding value for clinical observation of cirrhosis with different Child-push grades.