紫红獐牙菜化学成分研究

Chemical constituents of Swertia punicea Hemsl.

采用色谱分离手段对紫红獐牙菜(Swertia punicea Hemsl.)的乙醇提取物进行分离纯化,研究其化学成分,并运用1H NMR、13C NMR等波谱方法和文献数据对比鉴定化合物结构,从紫红獐牙菜全草中得到8个已知化合物,分别鉴定为:1,5-二羟基-2,3,4-三甲氧基酮(1)、1,7-二羟基-2,3,5-三甲基酮(2)、5,7,4'-三羟基黄酮(3)、β-谷甾醇(4)、豆甾醇(5)、2,5-di-O-β-D-glucopyranosyloxy-1,3-dimethoxybenzene(6)、7-(3-hydroxy-5-methoxyphenyl)propane-7,8,9-triol(7)、1-tetratriacontanol(8).

Ethanol extract of S. Punicea were separated and purified by chromatographic techniques in the study of the chemical constituents of Swertia punicea Hemsl.,the structures of these compounds were identified by spectroscopic analysis and compared with the data reported in the relevant literature. 8 compounds were isolated and identified as 1,5-dihydroxy-2,3,4-trimethoxyxanthone（ 1）,1,7-dihydroxy-2,3,5-trimethoxyxanthone（ 2）,5,7,4＇-trihydroxyflavone（ 3）,β-sitosterol（ 4）,stigmasterol（ 5）,2,5-di-O-β-D-glucopyranosyloxy-1,3 dimethoxybenzene（ 6）,7-（ 3-hydroxy-5-methoxyphenyl） propane-7,8,9-triol（ 7）,and 1-tetratriacontanol（ 8）.