抗抑郁剂在双相抑郁治疗中的合理应用

Rational use of antidepressants in bipolar depression

双相障碍是一种易共病、易误诊疾病,在抑郁期的治疗较为困难。目前抗抑郁剂被普遍用于双相抑郁的治疗,它们种类繁多,药理特性也不尽相同。临床治疗应在了解不同抗抑郁剂特点的基础上,结合患者实际情况实现个体化用药。该文对双相抑郁的治疗现状,尤其是抗抑郁剂的使用问题进行了分析讨论,以期为临床治疗提供参考。

Bipolar disorder is a serious psychiatric disease for its tendency towards co-morbidity,misdiagnose and poor curative effect for depression episodes.Antidepressants with various types and different pharmacological properties are widely used in the treatment of bipolar depression.Individualized medication should be used considering properties of different antidepressants and patients＇ own conditions.This article analyzed the current situation for the treatment of bipolar depression,especially the use of antidepressants,so as to provide reference for clinical treatment.