椎间盘源性下腰痛研究进展

Research progress of discogenic low back pain

腰痛是临床极为常见的一种不适症状,影响患者的生活质量。在各种因素导致的腰痛中,以椎间盘源性最为显著。由于椎间盘源性疼痛的机制尚不清楚,其临床表现不典型,因此其诊断和治疗仍然是一个挑战。虽然磁共振成像作为椎间盘腰痛诊断的间接指征。但是,该方法的敏感性较低,而且假阳性及假阴性较高降低了磁共振筛查的价值。值得一提的是椎间盘造影的应用大大提高了对椎间盘源性疼痛患者的诊断阳性率。此外,伴随医疗技术的进步临床中对于椎间盘源性下腰痛的治疗也出现了多种选择,包括:保守治疗、手术治疗、微创治疗以及现代化的生物治疗技术等。但是大多数疗法的价值尚未确定,需要更多的研究来确定各种疗法的临床价值。本文将综述椎间盘源性下腰痛的发病机制、诊断以及治疗方式的最新研究进展。

Low back pain is a very common clinical symptom,which affects the quality of life of patients.Intervertebral disc is the most significant factor in lumbago caused by various factors.Due to the unclear mechanism and untypicalclinical manifestations of intervertebral disc pain,its diagnosis and treatment is still a challenge.Although the high intensity zone with magnetic resonance imaging is an indirect indication for the diagnosis of low back pain.The low sensitivity,false positive and false negative of the method reduces the value of magnetic resonance imaging screening.It is worth mentioning that the application of discography has greatly improved the diagnostic positive rate of patients with intervertebral disc pain.In addition,with the progress of medical technology,many options for the treatment of lumbar discogenic low back pain can be chosen,including conservative treatment,surgical treatment,minimally invasive treatment and modern biological therapy.However,the value of most therapies has not yet been determined,and more research is needed to determine the clinical value of various therapies.This article will describe the latest research progress in the pathogenesis,diagnosis and treatment of discogenic low back pain.