小泛素样修饰蛋白化修饰在周围神经损伤再生过程中作用的研究进展

Research progress of sumoylation in the regeneration of peripheral nerve injury

小泛素相关修饰蛋白（SUMOs）是近年来新发现的一类重要的蛋白质翻译后修饰蛋白，类泛素化修饰（Sumoylation）在人体多种生物学活动过程中发挥重要作用。周围神经损伤临床常见，损伤后修复再生是一个相当复杂的过程，本文拟对SUMO化修饰在周围神经损伤再生过程中作用的最新研究作一综述。

Small ubiquitin-related modifiers （SUMOs） are discovered in recent years as a kind of important protein involved in the post-translational protein modification, and sumoylation plays an important role in a variety of biological processes in the human body. Peripheral nerve injuries are common in clinic, and the regeneration after injury is a rather complicated process. This article will review the latest research on the role of SUMO modification in the regeneration of peripheral nerve injury.