摘要
生物力学在椎间盘退变中扮演重要角色,二者相互影响,互为因果。为探索其机制,长时间以来许多学者进行了深入研究,尤其近年来有限元分析研究的广泛开展,突破了经费、材料、标本等多种限制,取得了许多新的成果。同时有学者尝试探索应用中医药延缓或阻止椎间盘退变,细胞生物学研究表明,中药成分制剂及复方制剂对体外培养的椎间盘细胞退变存在抑制作用。
Biomechanics plays an important role in intervertebral disc degeneration(IVDD), which impact each other, and is reciprocal causation. For long time many experts have researched this problem deeply, especially recent study by finite element analysis is widely developing, which is breaking through the limits by fund, material, sample and other restrictions, obtaining many achievements. Hunting for solution, some scholars have tried to delay or suspend this degenerative progress by using traditional Chinese medicine. The result of cytobiology test shows that some ingredient or compound of traditional Chinese medicine can inhibit intervertebral disc degeneration.
作者
祝永刚
孙旗
陈江
刘志超
郭菲宇
肖辉灯
柳根哲
ZHU Yong-gang;SUN Qi;CHEN Jiang;LIU Zhi-chao;GUO Fei-yu;XIAO Hui-deng;LIU Gen-zhe(Beijing Chinese Traditional Medicine Hospital Affiliated to Capital Medical University,Beijing 100010,China;The First Clinical Medicine College,Beijing Chinese Traditional Medicine University,Beijing 100700,China)
出处
《中国矫形外科杂志》
CAS
CSCD
北大核心
2018年第15期1400-1404,共5页
Orthopedic Journal of China
基金
北京市自然科学基金项目(编号:7142076)
关键词
椎间盘退变
邻近节段退变
生物力学
有限元分析
中医药
intervertebral disc degeneration
adjacent segment degeneration
biomechanics
finite element analysis
traditional Chinese medicine