摘要
口腔疣状癌(oral verrucous carcinoma,OVC)是一种具有独特组织学改变和生物学行为,有别于口腔鳞状细胞癌(oral squamous cell carcinoma,OSCC)的恶性肿瘤,发病原因目前尚不明确。研究发现,其首次临床诊断符合率仅为35%,常被误诊为疣状增生、牙源性角化囊肿、侵袭性牙周炎和慢性颌骨骨髓炎等疾病。OVC的治疗手段和预后与OSCC不尽相同,误诊和误治严重影响患者的生存质量。制定OVC临床诊治专家共识的目的 ,是希望减少OVC误诊误治,提高早期诊断率、患者生存率和生活质量。
Oral verrucous carcinoma（OVC） is a malignant tumor with independent histological changes and biological behaviors different from those of oral squamous cell carcinomas（OSCC）. Its etiology is still unclear. It has the first clinical diagnosis coincidence rate of only 35% and is often misdiagnosed as other oral diseases such as verrucous hyperplasia,odontogenic keratocyst, aggressive periodontitis and chronic osteomyelitis. The treatment and prognosis of OVC are different from those of OSCC. Its misdiagnosis and mistreatment seriously affect patients＇ quality of life. In order to reduce misdiagnosis and mistreatment of OVC and to improve its early diagnostic rate, patients＇ survival rate and quality of life, it is necessary to establish an expert consensus on this tumor according to the national clinical conditions.
作者
唐瞻贵
步荣发
刘彦普
郭伟
孙沫逸
郑家伟
何悦
尚政军
吴煜农
李劲松
韩正学
田臻
张陈平
李铁军
钟鸣
廖贵清
沈子华
黄俊辉
喻建军
苏彤
姚志刚
胡延佳
TANG Zhan-gui;BU Rong-fa;LIU Yan-pu;GUO Wei;SUN Mo-yi;ZHENG Jia-wei;HE Yue;SHANG Zheng-jun;WU Yu-nong;LI Jin-song;HAN Zheng-xue;TIAN Zhen;ZHANG Chen-ping;LI Tie-jun;ZHONG Ming;LIAO Gui-qing;SHEN Zi-hua;HUANG Jun-hui;YU Jian-jun;SU Tong;YAO Zhi-gang;HU Yah-jia(Department of Oral and Maxillofacial Surgery,Xiangya School of Stomatology,Central South University.Changsha 410013,Hunan Province;Deportment of Oral and Maxillofacial Surgery,China PLA General Hospital.Beo＇ing 100853;Department of Oral and Maxillofacial Surgery,School of Stomatology,The Fourth Military Medical University.Xi＇an 710032,Shaanxi Province;Department of Oromaxillofacial Head and Neck Oncology,Shanghai Ninth People ＇s Hospital,College of Stomatology,Shanghai Jioo Tong University School of Medicine.Shanghai 200011;Department of Oral and Moxillofacial Surgery,School of Stomatalogy,Wuhan University.Wuhan 430072,Hubei Province;Department of Oral and Maxillofacial Surgery,Hospital of Stomatology,Nanjing Medical University.Nanjing 210029,Jiangsu Province;Department of Oral and Maxillofacial Surgery,Sun Yat-sen Memorial Hospital,Sun Yat-sen University.Guangzhou 510120,Guangdong Province;Department of Oral and Maxillofacial Surgery,Hospital of Stomatology,Capital Medical University.Beijing 100050;Department of Oral Pathology,Shanghai Ninth People ＂s Hospital,College of Stomatology,Shanghai Jiao Tong University School of Medicine.Shanghai 200011;Department of Oral Pathology,School of Stomatology,Peking University.Belling 100081;Department of Oral Pathology,School of Stomatology,China Medical University.Shenyang 110122,Liaoning Province;Department of Oral and Maxillofacial Surgery,Hospital of Stomatology,Sun Yat sen University.Guangzhou 510055,Guangdong Province;Department of Oral Pathology,Xiangya School of Stomatology,Central South University.Changsha 410013,Hunan Province;Department of Head and Neck Surgery,Hunan Provincial Tumor Hospital.Changsha 410006,Hunan Province;Department of Oral and MaxiUofacial Surgery,Xiangya Hospital,Central South University.Changsha 410008,Hunan Province,China)
出处
《中国口腔颌面外科杂志》
CAS
2018年第4期362-370,共9页
China Journal of Oral and Maxillofacial Surgery
基金
国家自然科学基金(81671003)
湖南省科技计划(2014SK4006)
关键词
口腔疣状癌
临床诊治
专家共识
Oral verrucous carcinoma
OVC
Clinical diagnosis and management
Expert consensus
