红霉素联合阿奇霉素序贯疗法与单用阿奇霉素治疗小儿支原体肺炎的效果比较

Comparison of the effect of erythromycin combined with Azithromycin Sequential Therapy and azithromycin alone in the treatment of mycoplasma pneumonia in children

目的:探讨红霉素联合阿奇霉素序贯疗法与单用阿奇霉素治疗小儿支原体肺炎的效果。方法:选取2015年11月至2017年2月我院治疗的支原体肺炎患儿200例,随机分为两组,对照组使用阿奇霉素治疗,实验组在阿奇霉素治疗的基础上,加用红霉素静脉滴注,观察两组患儿症状改善情况。结果:实验组患儿咳嗽、发热及肺部啰音消失时间显著低于对照组,有统计学差异(P<0.05)。实验组100例中,有94例遵医嘱完成了治疗过程,依从率94%,对照组有93例完成了治疗,依从率93%,两组比较无统计学差异(P>0.05);实验组出现消化道等不良反应有12例,不良反应发生率12%,对照组发生率11%,两组比较无统计学差异(P>0.05)。结论:红霉素联合阿奇霉素序贯疗法治疗小儿支原体肺炎,具有更好的治疗效果。

To investigate the effect of erythromycin combined with Azithromyein Sequential Therapy and azithromycin alone in the treatment of mycoplasma pneumonia in children.Methods： fromNovember 2015 to February 2017 to a hospital for treatment of children with mycoplasma pneumonia in 200 cases,were randomly divided into two groups, the control group were treated with azithromycin.The patients in the experimental group based on the use of azithromycin treatment, the children were treated with erythromycin intravenously, the two groups were observed in pulmonary symptoms.Results： the improvement of cough time, fever disappearance time and tales disappear time in the experimental group were significantly lower than those in the control group（P〈0.05）.The experimental group of 100 cases,94 cases according to the doctor completed the treatment process,the compliance rate of 94% ,93 cases in the control group completed the treatment compliance rate of 93%, the two groups had no statistical difference（P〉0.05）;the experimental group appeared adverse reaction of digestive tract in 12 cases, the incidence of adverse reactions was 12 %, the control group the incidence rate of 11%, the two groups had no statistical difference（P〉0.05）.Conclusion： Azithromycin combined with erythromycin is effective in the treatment of children with Mycoplasma pneumoniae pneumonia.