病程12个月及以上非小细胞肺癌患者生活质量评估及影响因素研究

Influencing factors for quality of life in patients over 12 months after diagnosis of non-small cell lung cancer

目的·评估首诊至调查时间病程≥12个月的非小细胞肺癌(non-small cell lung cancer,NSCLC)患者的生活质量,探讨相关影响因素。方法·采用FACT-L(Functional Assessment of Cancer Therapy–Lung)量表对111名纳入研究的患者的生活质量进行评价,自制问卷收集患者人口学特征、医疗信息和情绪感受。结果·研究从治疗及患者主观感受2个路径探讨NSCLC患者生活质量的影响因素。单因素Logistic回归分析显示低生活质量的风险因素为:自卑孤独感、骨转移、病理类型、化学治疗周期、年龄、共住家庭成员结构和经济困难。结论·肺癌患者生活质量影响因素多元而广泛,情绪及症状管理亟待重视。

Objective·To examine quality of life and its influencing factors in patients over 12 months after diagnosis of non-small cell lung cancer（NSCLC）.Methods·A total of 111 patients included in the study completed the self-reported measures.Quality of life was measured using Functional Assessment of Cancer Therapy–Lung.Other measures included socio-demographic characteristics,disease-and treatment-related information,and emotional feelings.Results·The factors influencing the quality of life of NSCLC patients were investigated from two approaches：treatment and subjective feeling.Univariate Logistic regression analysis found the risk factors for low quality of life included sense of low self-esteem and loneliness,bone metastasis,pathological type,chemotherapy cycle,age,cohabitant type and financial burden.Conclusion·The factors associated with quality of life in lung cancer patients are diverse and extensive,and it warrants attention on psychological support and symptom management for these patients.