摘要
随着器官移植技术的提高和免疫抑制剂的广泛应用,移植器官或受者移植物的存活率增加,同时移植术后恶性肿瘤发生的风险也升高。由于其治疗需同时考虑到恶性肿瘤和移植器官功能,且有关此类群体的临床研究较少,其治疗方案尚未形成共识,亟需积累针对性的大规模临床观察和研究。本文拟探讨和总结近年来肾移植术后乳腺癌的临床特点、免疫抑制剂应用、治疗等相关因素。
With the improvement of organ transplantation technology and the widespread use of immunosuppressive agents,the survival rate of transplanted organs or recipient transplants has increased,and the risk of malignancy after transplantation has also increased. Because the treatment needs to take into account both the malignancy and the function of the transplanted organ,and there are few clinical studies on such groups,the treatment plan has not yet reached consensus,and it is urgent to accumulate targeted large-scale clinical observations and studies. This article intends to explore and summarize the clinical features of breast cancer after renal transplantation in recent years,the application of immunosuppressive agents,treatment and other related factors.
作者
宋田利
张一帆
张颖超
王丹
张金香
徐景伟
SONG Tian-Li;ZHANG Yi-Fan;ZHANG Ying-Chao;WANG Dan;ZHANG Jin-Xiang;XU Jing-Wei(Department of Breast Surgery,the Second Hospital of Jilin University,Changchun 130041,China)
出处
《中国免疫学杂志》
CAS
CSCD
北大核心
2018年第7期1108-1113,共6页
Chinese Journal of Immunology
基金
国家自然科学青年科学基金项目(C060406)
吉林省科技厅国际科技合作项目(20180414035GH)
吉林省科技厅优秀青年人才基金项目(20180520229JH)资助
关键词
肾移植
乳腺癌
免疫抑制剂
Renal transplantation
Breast cancer
Immunosuppressive agent