摘要
Neuroimaging has opened new opportunities to study the neural correlates of consciousness, and provided additional information concerning diagnosis, prognosis, and therapeutic interventions in patients with disorders of consciousness. Here, we aim to review neuroimaging studies in chronic disorders of consciousness from the viewpoint of the brain network, focusing on positron emission tomogra- phy, functional MRI, functional near-infrared spectroscopy, electrophysiology, and diffusion MRI. To accelerate basic research on disorders of consciousness and provide a panoramic view of unconsciousness, we propose that it is urgent to integrate different techniques at various spatiotemporal scales, and to merge fragmented findings into a uniform ＂Brainnetome＂ （Brain-net-ome） research framework.
Neuroimaging has opened new opportunities to study the neural correlates of consciousness, and provided additional information concerning diagnosis, prognosis, and therapeutic interventions in patients with disorders of consciousness. Here, we aim to review neuroimaging studies in chronic disorders of consciousness from the viewpoint of the brain network, focusing on positron emission tomogra- phy, functional MRI, functional near-infrared spectroscopy, electrophysiology, and diffusion MRI. To accelerate basic research on disorders of consciousness and provide a panoramic view of unconsciousness, we propose that it is urgent to integrate different techniques at various spatiotemporal scales, and to merge fragmented findings into a uniform ＂Brainnetome＂ （Brain-net-ome） research framework.
基金
supported by the National Natural Science Foundation of China(81471380,31771076,81501550,91432302,31620103905,and 81501179)
the Science Frontier Program of the Chinese Academy of Sciences(QYZDJSSW-SMC019)
National Key R&D Program of China(2017YFA0105203,2017YFB1002502)
Beijing Municipal Science and Technology Commission(Z161100000216152,Z161100000216139,Z171100000117002,and Z161100000516165)
the Shenzhen Peacock Plan(KQTD2015033016104926)
the Guangdong Pearl River Talents Plan(2016ZT06S220)
Youth Innovation Promotion Association,CAS,China
