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血清降钙素原水平监测指导老年心力衰竭合并肺炎患者抗感染治疗效果观察 被引量:5

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摘要 目的观察血清降钙素原(PCT)水平监测指导老年心力衰竭(心衰)合并肺炎患者抗感染治疗的效果。方法选取医院收治的86例老年心衰合并肺炎患者作为研究对象,按照随机数字表法将其分为研究组和对照组,各43例,2组患者均行常规对症治疗,研究组在常规治疗基础上行血清降钙素原水平监测下指导抗感染治疗,对照组在常规治疗基础上行常规抗感染治疗。对比2组治疗前后的C反应蛋白(CRP)水平、红细胞沉降率(ESR)水平及病原菌阳性率。结果治疗前2组CRP、ESR水平比较差异均无统计学意义(P>0.05),治疗后2组CRP、ESR水平均明显下降,但研究组下降幅度更明显,差异有统计学意义(P<0.05)。2组病原菌阳性率比较差异无统计学意义(χ2=0.1911,P=0.6619)。结论应用PCT监测指导老年心衰合并肺炎患者抗感染治疗的效果较好,能有效降低患者CRP与ESR水平,值得临床进一步推广应用。
作者 王保明
出处 《临床合理用药杂志》 2018年第22期133-134,共2页 Chinese Journal of Clinical Rational Drug Use
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