小柴胡汤治疗小儿流行性感冒有效性及安全性观察

Observation on Efficacy and Safety of Xiao Chaihu Decoction in Treating Children's Influenza

目的:观察小柴胡汤治疗小儿流行性感冒的临床疗效及不良反应。方法:流行性感冒患儿90例,随机分为2组各45例,观察组采用小柴胡汤治疗,对照组采用常规西医治疗,两组患儿均连续治疗7d。比较两组患儿临床疗效及药物不良反应。结果:2组疗效无统计学差异;观察组完全退烧时间、临床痊愈时间均显著低于对照组(P<0.05);观察组患儿不良反应发生率显著低于对照组(P<0.05)。结论小柴胡汤治疗小儿流行性感冒临床疗效显著,不良反应少,值得临床推广。

Objective To observe the clinical efficacy and adverse reactions of Xiao Chaihu Decoction in the treat- ment of children with influenza. Method 90 children with influenza in our hospital form October 2017 to February 2018 were selected as the research subject, The children were randomly divided into observation group （ 45 cases were given Xiaochaihu Decoction treatment and conventional group （ 45 cases were given routine western medicine ）, compared two groups of clinical efficacy and adverse drug reaction. Result There was no statistical difference between the obser- vation group and the control group [95.56% vs.93.33%, P〉0.05], the time of complete fever and clinical recovery time in the observation group [ （ 54.30 ± 4.40 ） h vs. （ 80.40 ± 12.60 ） h, P〈0.05], [ （ 35.20 ± 2.50 ） h vs. （ 60.40 ± 5.45 ） h, P〈0.05], which were all significantly lower than the control group; the adverse reactions of the children in the observation group were all significantly lower than those in the control group. The rate was significantly lower than that of the control group [2.22% vs.24.44%, P〈0.05].Conclusion Xiao Chaihu Decoction has significant clinical effect in treating children＇ s influenza, and has few adverse reactions. It is worthy of clinical promotion..