认知行为干预对肺癌化疗患者癌性疲乏及生活质量的影响

Influence of cognitive-behavioral intervention on cancer-related fatigue and life quality in patients treated with chemotherapy of lung cancer

目的探讨认知行为干预对肺癌化疗患者癌性疲乏及生活质量的影响。方法选取2016年1月~2017年10月在我院化疗的肺癌患者共90例,随机分为观察组与对照组各45例。两组患者均予以常规肺癌化疗,对照组患者予以常规干预,观察组患者在对照组基础上予以认知行为干预。两组患者均干预6个月,分别在干预前后评估癌性疲乏及生活质量情况。结果干预6个月后,两组患者PES评分均较干预前明显下降(P<0.05或P<0.01),且治疗后观察组下降幅度较对照组更显著(P<0.05);两组患者生活质量SF-36评分均较干预前明显上升(P<0.05或P<0.01),且观察组患者上升幅度较对照组更显著(P<0.05)。结论认知行为干预用于肺癌化疗患者的疗效优于常规干预,能显著减轻患者的癌性疲乏症状,改善患者生活质量。

Objective To investigate the influence of cognitive-behavioral intervention on cancer-related fatigue and life quality in patients treated with chemotherapy of lung cancer. Methods 90 patients with lung cancer and treated with chemotherapy in our hospital from January, 2016 to October, 2017 were selected and randomized into observation group and control group with 45 patients in each. Patients in two groups were treated with routine chemotherapy of lung cancer. Patients in control group were treated with conventional intervention and patients in observation group were treated with additional cognitive-behavioral intervention. The interventions lasted 6 months in two groups of patients. Cancer-related fatigue and life quality before and after interventions were evaluated. Results After 6-month intervention, scores of PES in two groups decreased significantly when compared with those before intervention（P〈0.05, P〈0.01）. Score of PES in observation group decreased more significantly than that in control group（P〈0.05）. Scores of SF-36, the score of life quality, in two groups increased significantly when compared with those before intervention（P〈0.05, P〈0.01）. Score of SF-36 in observation group increased more significantly than that in control group （P〈0.05）. Conclusion The effectiveness of cognitive-behavioral intervention in patients treated with chemotherapy of lung cancer was better than that of conventional intervention. Cognitive-behavioral intervention could alleviate the symptoms of cancer-related fa- tigue significantly and improve life quality.