iCare HOME眼压计测量眼压的准确性评估

Evaluation of accuracy of measuring intraocular pressure using iCare HOME tonometer

目的通过比较iCare HOME眼压计与Goldmann压平眼压计(GAT)、非接触眼压计(NCT)测量眼压结果的差异和相关性,评估iCare HOME眼压计测量眼压的准确性。设计诊断试验。研究对象青光眼(48例77眼)、可疑青光眼(8例13眼)、白内障(16例23眼)及正常体检者(4例7眼)共76例(120眼)进行眼压测量。方法所有受检者使用iCare HOME眼压计、GAT和NCT测量眼压,并根据GAT测量的眼压结果进行分组(A组:眼压<16 mmHg;B组:16~21 mmHg;C组:>21 mmHg)。采用单因素方差分析、Bland-Altman分析和线性相关分析比较iCare HOME、GAT和NCT测量结果的一致性和相关性。主要指标眼压。结果使用iCare HOME、GAT和NCT测量结果平均值分别为(18.32±6.52)mmHg、(18.14±5.82)mmHg和(19.10±5.85)mmHg(F=0.846,P=0.430)。iCare HOME与GAT、iCare HOME与NCT和GAT与NCT测量相关系数r分别为0.947、0.961和0.937(P均<0.01)。三种眼压计测量结果在不同眼压水平差值不同,iCare HOME与GAT的差异随着眼压的增高而增大,而iCare HOME与NCT的差异随着眼压的增高而减小。Bland-Altman分析证明三种眼压计之间具有良好的一致性。结论 iCare HOME眼压计测量眼压的准确性良好,与GAT、NCT测量结果之间具有良好的相关性和一致性。

Objective To evaluate the accuracy of iCare HOME tonometer measuring intraocular pressure（IOP） at different levels compared with Goldmann applanation tonometer （GAT） and non-contact tonometer （NCT）. Design Diagnostic trial. Participants A total of 120 eyes of 76 patients or normal subjects in Shenyang Aier Eye Hospital were examined, including glaucoma （77 eyes of 48 pa-tients）, glaucoma suspect （13 eyes of 8 patients）, cataract patients （23 eyes of 16 patients） and normal subjects （7 eyes of 4 subjects）. Methods All participants＇ IOP was measured with iCare HOME, GAT and NCT, and grouped according to the results of GAT （group A： IOP 〈16 mmHg, group B： 16-21 mmHg, group C： 〉21 mmHg）. One-way ANOVA, Bland-Altman analysis and linear correlation analysis were used to compare the consistency and correlation of iCare HOME, GAT and NCT measurements. Main Outcome Measures IOP. Results The mean IOP measured with iCare HOME, GAT and NCT was （18.32±6.52） mmHg, （18.14±5.82） mmHg and （19.10±5.85） mmHg respectively （F=0.846, P=0.430）. The correlation coefficients （r） of iCare HOME and GAT, iCare HOME and NCT, GAT and NCT was 0.947, 0.961 and 0.937 （all P〈0.01） respectively. The results of three types of tonometer were different with different IOP lev-els. The difference between iCare HOME and GAT increased with the increase of IOP, while the difference between iCare HOME and NCT decreased with the increase of IOP. Bland-ahman analysis showed that there was a good consistency between the three types of IOP measurement. Conclusion The accuracy of iCare HOME is good for the measurement of IOP, and it is consistent with GAT and NCT measurements. （Ophthalmol CHN, 2018, 27： 286-290）