无淋巴结转移胃癌患者预后分析

An analysis of prognosis of patients with gastric cancer without lymphatic metastasis

目的探讨无淋巴结转移胃癌患者的预后及其影响因素。方法 150例无淋巴结转移胃癌患者,采用Kaplan-Meier法和Log-rank检验分析患者的预后,Cox比例风险回归模型分析预后影响因素。结果 150例胃癌患者随访时间1～95个月,中位生存时间68个月,术后1、3和5年生存率分别为80%、69%和63%。患者的性别、年龄、手术方式、肿瘤位置、脉管内癌栓和术后化疗均与预后无关(P>0.05),肿瘤直径、组织学类型和浸润深度均与预后有关(P<0.01)。Cox比例风险回归模型分析显示,肿瘤直径、组织学类型和浸润深度均是影响预后的独立因素(P<0.05)。结论肿瘤直径、组织学类型和浸润深度是无淋巴结转移胃癌患者预后的影响因素。

Objective To analyze the prognosis of the patients with gastric cancer without lymphatic metastasis.Methods The prognosis of 150 patients with gastric cancer without lymphatic metastasis was analysed by Kaplan-Meier and Log-rank test.The influencing factors related to the prognosis were analysed by Cox proportional risk regression model.Results The patients were followed up for 1-95 months and the median survival time was 68 months.The 1-,3-and 5-year overall survival rates were 80%,69% and 63%,respectively.The gender,age,operation method,tumor location,intravascular tumor thrombus and postoperative chemotherapy were not closely related to the prognosis（P〈0.05）,but the tumor diameter,histological type and infiltration depth were closely associated with the prognosis of patients（P〈0.01）.Cox proportional risk regression model analysis showed that the tumor diameter,histological type and infiltration depth were the independent influence factors for the prognosis（P〈0.05）.Conclusion The tumor diameter,histological type and infiltration depth are the factors influencing the prognosis of the patients with gastric cancer without lymphatic metastasis.