肝细胞肝癌微血管侵犯的MRI研究

The study of microvascular invasion of hepatocellular carcinoma with MRI

目的探讨肝细胞肝癌微血管侵犯(MVI)与MRI影像特征的相关性。方法回顾分析107例肝细胞肝癌患者的MRI动态增强图像,研究肿瘤大小、动脉期瘤周增强、肿瘤包膜、肿瘤边缘以及多灶性与肝细胞肝癌微血管侵犯的相关性。确定MVI的独立预测因子。结果 MVI阳性的有31.8%(34/107),MVI阴性的为68.2%(73/107)。两组之间动脉期瘤周增强、肿瘤包膜以及多灶性无统计学差异(P>0.05);肿瘤大小、肿瘤边缘有统计学差异(P<0.05)。结论肿瘤大于5cm和边缘不光滑可以术前预测肝细胞肝癌MVI。

Objective To investigate the correlation between Microvascular invasion （MVI） and MRI image features in in patients withhepatocellular carcinoma （HCC）. Methods The MRI dynamic congteast-enhanced images of 107 patients with hepatocellular carcinomawere reviewed retrospectively. The correlation between tumorsize, peritumoral arterial enhancement,tumor pseudo-capsule, tumormargins,multifocality and microvascular invasion of hepatocellular carcinoma were studied and independent predictors of MVI were determind. Results 31.8%（34/107） of the patients with HCC were confirmed as MVI-positive, and 68.2%（73/107） were as MVI-negative. There were no statistically significant difference between the two groups in peritumoral arterial enhancement, tumor pseudo-capsule and multifocality （ P 〉0.05）, and there were statistically significant difference in tumor size and tumor margin （ P 〈0.05）. Conclusion A tumor size 〉5 cm and a non-smooth tumor margin could be used as preoperative predictors of the presence of MVI in patients with HCC.