星蒌承气汤治疗缺血性中风病急性期痰热腑实证的临床疗效观察

Clinical Observation on Xinglou Chengqi Decoction in the Treatment of Acute Ischemic Stroke with Phlegm-heat Fu-sthenia Syndrome

目的观察星蒌承气汤治疗缺血性中风病急性期痰热腑实证的临床疗效。方法选择缺血性中风病急性期痰热腑实证病人82例,按随机数字表法分为治疗组(n=42)和对照组(n=40)。对照组给予神经内科常规治疗,治疗组在对照组基础上加用星蒌承气汤加减以化痰通腑,疗程10 d,比较两组治疗前后美国国立卫生研究院卒中量表(NIHSS)评分、日常生活能力(Barthel指数)差异。结果治疗后两组NIHSS评分较治疗前均降低(P<0.01),且治疗组降低更显著(P<0.05),差异有统计学意义。治疗后两组Barthel指数较治疗前均增加(P<0.01),且治疗组增加更显著,差异有统计学意义(P<0.05)。结论神经内科常规治疗基础上联合星蒌承气汤治疗缺血性中风病急性期痰热腑实证疗效确切。

Objective To investigate the effect of Xinglou Chengqi decoction（XCD）in the treatment of acute ischemic stroke with phlegmheat and fu-sthenia syndrome.Methods Eighty-two patients with acute ischemic stroke and phlegm-heat and fu-sthenia syndrome were randomly divided into two groups：control group（n =42）treated with routine treatment and treatment group（n =42）treated with XCD in the basis of routine treatment for 10 days.National Institutes of Health Stroke Scale（NIHSS）scores and Barthel index（BI）were observed in two groups before and after treatment.Results After treatment,the NIHSS scores in two groups were lower than those before treatment（P 〈0.01）,which were lower in treatment group than those in control group（P 〈0.05）.After treatment,BI in two groups were higher than those before treatment（P 〈0.01）,which were higher in treatment group than those in control group（P〈 0.05）.Conclusion XCD and routine treatment have the obvious curative effect on acute phase of ischemic stroke with phlegm-heat and fu-sthenia syndrome.